DESCRIPTION:Griess et al. 1993: HMG boxes were initially identified as DNA-binding domains of the human RNA polymerase I (pol I) transcription factor hUBF and the animal high-mobility-group (HMG) protein family HMG1.
Members of this family
SHOULD possess HMG_box domain
SHOULD NOT possess ARID YABBY domains
References
Grasser, KD; Teo, SH; Lee, KB; Broadhurst, RW; Rees, C; Hardman, CH; Thomas, JO. 1998. DNA-binding properties of the tandem HMG boxes of high-mobility-group protein 1 (HMG1). Eur. J. Biochem. 253(3):787-95 PUBMEDID:9654080
Griess, EA; Rensing, SA; Grasser, KD; Maier, UG; Feix, G. 1993. Phylogenetic relationships of HMG box DNA-binding domains. J. Mol. Evol. 37(2):204-10 PUBMEDID:8411210
Wissmüller, S; Kosian, T; Wolf, M; Finzsch, M; Wegner, M. 2006. The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors. Nucleic Acids Res. 34(6):1735-44 PUBMEDID:16582099