HB Family

DESCRIPTION:Kappen. 2000The homeodomain is a DNA-binding motif within transcription factor proteins. These transcription factors may be involved in cell differentiation and control of cell growth, as well as patterning of diverse organisms.

Members of this family

    SHOULD possess Homeobox KNOX1 KNOX2 domains

References

    Bharathan, G; Janssen, BJ; Kellogg, EA; Sinha, N. 1997. Did homeodomain proteins duplicate before the origin of angiosperms, fungi, and metazoa? Proc. Natl. Acad. Sci. U.S.A. 94(25):13749-53 PUBMEDID:9391098

    Chan, RL; Gago, GM; Palena, CM; Gonzalez, DH. 1998. Homeoboxes in plant development. Biochim. Biophys. Acta 1442(1):1-19 PUBMEDID:9767075

    Kappen, C. 2000. The homeodomain: an ancient evolutionary motif in animals and plants. Comput. Chem. 24(1):95-103 PUBMEDID:10642882

    Scott, MP; Tamkun, JW; Hartzell, GW. 1989. The structure and function of the homeodomain. Biochim. Biophys. Acta 989(1):25-48 PUBMEDID:2568852