DESCRIPTION:E2F-DP transcription factors are key components of the cyclin D/retinoblastoma/E2F pathway, they regulate the expression of genes required for G1/S transition and S-phase progression.
Members of this family
SHOULD possess E2F_TDP domain
References
de Jager, SM; Menges, M; Bauer, UM; Murra, JA. 2001. Arabidopsis E2F1 binds a sequence present in the promoter of S-phase-regulated gene AtCDC6 and is a member of a multigene family with differential activities. Plant Mol. Biol. 47(4):555-68 PUBMEDID:11669580
Zheng, N; Fraenkel, E; Pabo, CO; Pavletich, NP. 1999. Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DP. Genes Dev. 13(6):666-74 PUBMEDID:10090723