DESCRIPTION:Bouche et al. 2002: Screening of cDNA expression libraries derived from plants exposed to stress, with 35S-labeled recombinant calmodulin as a probe, revealed a new family of proteins containing a transcription activation domain and two types of DNA-binding domains designated the CG-1 domain and the transcription factor immunoglobulin domain, ankyrin repeats, and a varying number of IQ calmodulin-binding motifs. Based on domain organization and amino acid sequence comparisons, similar proteins, with the same domain organization, were identified in the genomes of other multicellular organisms including human, Drosophila, and Caenorhabditis, whereas none were found in the complete genomes of single cell eukaryotes and prokaryotes. This family of proteins was designated calmodulin-binding transcription activators (CAMTAs).
Members of this family
SHOULD possess CG-1 IQ domains
References
Bouché, N; Scharlat, A; Snedden, W; Bouchez, D; Fromm, H. 2002. A novel family of calmodulin-binding transcription activators in multicellular organisms. J. Biol. Chem. 277(24):21851-61 PUBMEDID:11925432